It's been known for some time that liberal use of antibiotics among both humans and agricultural animals has caused increasing resistance in bacteria of these remedies.
Now there's talk of the last line of defence falling, even as resistance continues to spread. A detailed explanation can be found here, written by Maryn McKenna, a science writer for National Geographic. A drug called colistin is being overcome by a resistance driven by a genetic change in bacteria that is also easily passed among bacteria, and appears to be spreading rapidly from China.
Where is this leading? According to Medical Daily 10M people a year could die of bacterial infections by 2050, up from thousands today. A bad trend.
Hopefully science will find alternatives, before our 70 year honeymoon with antibiotics is over. Before that time, people would routinely die from infections.